Lipid emulsion-mediated reversal of toxic-dose aminoamide local anesthetic-induced vasodilation in isolated rat aorta
BackgroundIntravenous lipid emulsion has been used to treat systemic toxicity of local anesthetics.The goals of this in vitro study were to determine the ability of two lipid emulsions (Intralipid® and Lipofundin® MCT/LCT) to reverse toxic dose local anesthetic-induced vasodilation in isolated rat aortas.MethodsIsolated endothelium-denuded aortas